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1.
Front Neuroinform ; 16: 1055241, 2022.
Article in English | MEDLINE | ID: covidwho-2246198

ABSTRACT

Harris Hawks optimization (HHO) is a swarm optimization approach capable of handling a broad range of optimization problems. HHO, on the other hand, is commonly plagued by inadequate exploitation and a sluggish rate of convergence for certain numerical optimization. This study combines the fireworks algorithm's explosion search mechanism into HHO and proposes a framework for fireworks explosion-based HHo to address this issue (FWHHO). More specifically, the proposed FWHHO structure is comprised of two search phases: harris hawk search and fireworks explosion search. A search for fireworks explosion is done to identify locations where superior hawk solutions may be developed. On the CEC2014 benchmark functions, the FWHHO approach outperforms the most advanced algorithms currently available. Moreover, the new FWHHO framework is compared to four existing HHO and fireworks algorithms, and the experimental results suggest that FWHHO significantly outperforms existing HHO and fireworks algorithms. Finally, the proposed FWHHO is employed to evolve a kernel extreme learning machine for diagnosing COVID-19 utilizing biochemical indices. The statistical results suggest that the proposed FWHHO can discriminate and classify the severity of COVID-19, implying that it may be a computer-aided approach capable of providing adequate early warning for COVID-19 therapy and diagnosis.

2.
IEEE Access ; 9: 45486-45503, 2021.
Article in English | MEDLINE | ID: covidwho-1522547

ABSTRACT

This paper has proposed an effective intelligent prediction model that can well discriminate and specify the severity of Coronavirus Disease 2019 (COVID-19) infection in clinical diagnosis and provide a criterion for clinicians to weigh scientific and rational medical decision-making. With indicators as the age and gender of the patients and 26 blood routine indexes, a severity prediction framework for COVID-19 is proposed based on machine learning techniques. The framework consists mainly of a random forest and a support vector machine (SVM) model optimized by a slime mould algorithm (SMA). When the random forest was used to identify the key factors, SMA was employed to train an optimal SVM model. Based on the COVID-19 data, comparative experiments were conducted between RF-SMA-SVM and several well-known machine learning algorithms performed. The results indicate that the proposed RF-SMA-SVM not only achieves better classification performance and higher stability on four metrics, but also screens out the main factors that distinguish severe COVID-19 patients from non-severe ones. Therefore, there is a conclusion that the RF-SMA-SVM model can provide an effective auxiliary diagnosis scheme for the clinical diagnosis of COVID-19 infection.

3.
IEEE Access ; 9: 17787-17802, 2021.
Article in English | MEDLINE | ID: covidwho-1105107

ABSTRACT

This study is devoted to proposing a useful intelligent prediction model to distinguish the severity of COVID-19, to provide a more fair and reasonable reference for assisting clinical diagnostic decision-making. Based on patients' necessary information, pre-existing diseases, symptoms, immune indexes, and complications, this article proposes a prediction model using the Harris hawks optimization (HHO) to optimize the Fuzzy K-nearest neighbor (FKNN), which is called HHO-FKNN. This model is utilized to distinguish the severity of COVID-19. In HHO-FKNN, the purpose of introducing HHO is to optimize the FKNN's optimal parameters and feature subsets simultaneously. Also, based on actual COVID-19 data, we conducted a comparative experiment between HHO-FKNN and several well-known machine learning algorithms, which result shows that not only the proposed HHO-FKNN can obtain better classification performance and higher stability on the four indexes but also screen out the key features that distinguish severe COVID-19 from mild COVID-19. Therefore, we can conclude that the proposed HHO-FKNN model is expected to become a useful tool for COVID-19 prediction.

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